Zaproszenie na kurs online Prof. Richarda Bowatera dla dyscypliny naukowej Nauki Medyczne i Nauki o Zdrowiu

 

Szkoła Doktorska UJK – Sekcja Nauk Medycznych i Nauk o Zdrowiu zaprasza na kurs online w języku angielskim, który poprowadzi Profesor Richard Bowater z Uniwersytetu Anglii Wschodniej (The University of East Anglia) w Norwich w ramach Projektu NAWA STER „Umiędzynarodowienie Szkoły Doktorskiej Uniwersytetu Jana Kochanowskiego w Kielcach”.

Temat kursu: ”Repetitive DNA sequences and their impact on nucleic acid structure and human disease”.


TERMINY:

03.11.2025 r.; 10.11.2025 r., 17.11.2025 r.; 24.11.2025

 

Platforma: Zoom

Dostęp do spotkania:

03 listopad 2025 r. godz. 10:30 – 13:00

https://zoom.us/j/92994723056

Identyfikator spotkania: 929 9472 3056

 

10 listopad 2025 r. godz. 10:30 – 13:00

https://zoom.us/j/98196539356

Identyfikator spotkania: 981 9653 9356

 

17 listopad 2025 r. godz. 10:30 – 13:00

https://zoom.us/j/93812007792

Identyfikator spotkania: 938 1200 7792

 

24 listopad 2025 r. godz. 10:30 – 13:00

https://zoom.us/j/99450970614

Identyfikator spotkania: 994 5097 0614

 

Poniżej przedstawiamy harmonogram kursu:


Schedule and brief description of the course

„REPETITIVE DNA SEQUENCES AND THEIR IMPACT ON NUCLEIC ACID STRUCTURE AND HUMAN DISEASE “

for Doctoral school UJK Kielce

 

Date: Time (polish time): Topic:
03.11.2025 10:30 – 13:00
  • Structure and Function of Nucleic Acids
10.11.2025 10:30 – 13:00
  • Contemporary Technologies to Study DNA Sequences and Gene Function
17.11.2025 10:30 – 13:00
  • Protein-Nucleic Acid Interactions
24.11.2025 10:30 – 13:00
  • Structure and Metabolism of DNA Repeat Sequences

 

Literature:

1.

– Bowater & Waller (2014): “DNA structure”, In “eLS”, John Wiley & Sons Ltd, Chichester, DOI: 10.1002/9780470015902.a0006002.pub2

– Bowater (2015) “Supercoiled DNA: Structure”, In “eLS”, John Wiley & Sons Ltd, Chichester, DOI: 10.1002/9780470015902.a0001040.pub3

– Bowater & Gates (2015) Nucleotides: Structure and Properties”, In “eLS”, John Wiley & Sons Ltd, Chichester, DOI: 10.1002/9780470015902.a0001333.pub3

– Brazda, Fojta & Bowater (2020) “Structures and Stability of Simple DNA Repeats from Bacteria”, Biochemical Journal, 477, pp. 325-339

2.

– Brazda, Bartas & Bowater (2021) “Evolution of diverse strategies for promoter regulation”, Trends in Genetics, 37, pp. 730-744

– Li & Durbin (2024) “Genome assembly in the telomere-to-telomere era”, Nature Reviews Genetics, 25, pp. 658–670

– Mardis & Wilson (2025) “Tracing the evolution of sequencing into the era of genomic medicine”, Nature Reviews Genetics, 26, pp. 719–734

3.

– Bowater, Cobb, Pivonkova, Havran & Fojta (2015) “Biophysical and electrochemical studies of protein-nucleic acid interactions”, Monatshefte für Chemie – Chemical Monthly, 146, pp. 723-739

– Pergolizzi, Wagner & Bowater (2016) “Biochemical and structural characterization of DNA ligases from bacteria and archaea”, Bioscience Reports, 36, e00391

– Bowater, Bohálová & Brazda (2022) “Interaction of proteins with inverted repeats and cruciform structures in nucleic acids”, International Journal of Molecular Sciences, 23 (11), 6171

4.

– Bohálová, Bowater & Brazda (2022) “New telomere to telomere assembly of human chromosome 8 reveals a previous underestimation of G-quadruplex forming sequences and inverted repeats”, Gene, 810, pp. 146058

– Brazda, Bowater, Pečinka & Bartas (2025) “Noncanonical nucleic acid structures—powerful but neglected antiviral targets”, mBIO, pp. e02730-25

– Dobrovolná, Bowater, Pečinka, Brazda & Bartas (2025) “High-resolution assembly of the human Y chromosome identifies a vast landscape of inverted repeats associated with structural and functional genomic features”, International Journal of Molecular Sciences, in press


Serdecznie zapraszamy i liczymy na Państwa udział!