Invitation to the Online Course by Prof. Richard Bowater for the discipline: Medical and Health Sciences

 

The Doctoral School of Jan Kochanowski University in Kielce – Section of Medical and Health Sciences
cordially invites you to an online course (in English) conducted by Professor Richard Bowater from the University of East Anglia in Norwich (United Kingdom).

The course is organized within the framework of the NAWA STER Project “Internationalization of the Doctoral School of Jan Kochanowski University in Kielce.”

Course topic:Repetitive DNA sequences and their impact on nucleic acid structure and human disease”.

DATES:

3 November 2025; 10 November 2025; 17 November 2025; 24 November 2025

 

Platform: Zoom

Access to meetings:

3 November 2025 – 10:30 a.m. – 1:00 p.m.

https://zoom.us/j/92994723056

Meeting ID: 929 9472 3056

 

10 November 2025 – 10:30 a.m. – 1:00 p.m.

https://zoom.us/j/98196539356

Meeting ID: 981 9653 9356

 

17 November 2025 – 10:30 a.m. – 1:00 p.m.

https://zoom.us/j/93812007792

Meeting ID: 938 1200 7792

 

24 November 2025 – 0:30 a.m. – 1:00 p.m.

https://zoom.us/j/99450970614

Meeting ID: 994 5097 0614

 

Below is the course schedule:

Schedule and brief description of the course

„REPETITIVE DNA SEQUENCES AND THEIR IMPACT ON NUCLEIC ACID STRUCTURE AND HUMAN DISEASE “

for Doctoral school UJK Kielce

 

Date: Time (polish time): Topic:
03.11.2025 10:30 – 13:00
  • Structure and Function of Nucleic Acids
10.11.2025 10:30 – 13:00
  • Contemporary Technologies to Study DNA Sequences and Gene Function
17.11.2025 10:30 – 13:00
  • Protein-Nucleic Acid Interactions
24.11.2025 10:30 – 13:00
  • Structure and Metabolism of DNA Repeat Sequences

 

Literature:

1.

– Bowater & Waller (2014): “DNA structure”, In “eLS”, John Wiley & Sons Ltd, Chichester, DOI: 10.1002/9780470015902.a0006002.pub2

– Bowater (2015) “Supercoiled DNA: Structure”, In “eLS”, John Wiley & Sons Ltd, Chichester, DOI: 10.1002/9780470015902.a0001040.pub3

– Bowater & Gates (2015) Nucleotides: Structure and Properties”, In “eLS”, John Wiley & Sons Ltd, Chichester, DOI: 10.1002/9780470015902.a0001333.pub3

– Brazda, Fojta & Bowater (2020) “Structures and Stability of Simple DNA Repeats from Bacteria”, Biochemical Journal, 477, pp. 325-339

2.

– Brazda, Bartas & Bowater (2021) “Evolution of diverse strategies for promoter regulation”, Trends in Genetics, 37, pp. 730-744

– Li & Durbin (2024) “Genome assembly in the telomere-to-telomere era”, Nature Reviews Genetics, 25, pp. 658–670

– Mardis & Wilson (2025) “Tracing the evolution of sequencing into the era of genomic medicine”, Nature Reviews Genetics, 26, pp. 719–734

3.

– Bowater, Cobb, Pivonkova, Havran & Fojta (2015) “Biophysical and electrochemical studies of protein-nucleic acid interactions”, Monatshefte für Chemie – Chemical Monthly, 146, pp. 723-739

– Pergolizzi, Wagner & Bowater (2016) “Biochemical and structural characterization of DNA ligases from bacteria and archaea”, Bioscience Reports, 36, e00391

– Bowater, Bohálová & Brazda (2022) “Interaction of proteins with inverted repeats and cruciform structures in nucleic acids”, International Journal of Molecular Sciences, 23 (11), 6171

4.

– Bohálová, Bowater & Brazda (2022) “New telomere to telomere assembly of human chromosome 8 reveals a previous underestimation of G-quadruplex forming sequences and inverted repeats”, Gene, 810, pp. 146058

– Brazda, Bowater, Pečinka & Bartas (2025) “Noncanonical nucleic acid structures—powerful but neglected antiviral targets”, mBIO, pp. e02730-25

– Dobrovolná, Bowater, Pečinka, Brazda & Bartas (2025) “High-resolution assembly of the human Y chromosome identifies a vast landscape of inverted repeats associated with structural and functional genomic features”, International Journal of Molecular Sciences, in press


We cordially invite you to participate and look forward to your attendance.